Idris Mbombo, Jackson Mwanza, Misheck Chaila and Simon Silwimba are all out for Zesco United’s CAF Confederation Cup clash with Enugu Rangers.
The first leg of play-off round tie sees the 2015 Zambian league champions travelling to Nigeria for the showdown on Saturday.
While Mbombo is suspended, fellow marksman Mwanza as well as midfielder Misheck Chaila and defender Simon Silwimba are all injured.
“We have Jackson, Simon and Chaila who are all injured,” head coach Zlatko Krmpotic told SuperSport.
“Mbombo is also suspended but, this is football we must prepare other players to play in Nigeria.”
Silwimba hurt his groin against Le Messager Ngozi of Burundi on March 10, while Chaila injured his right knee on a Zambian training camp just over a week ago.
Mwanza sustained a swollen ankle last weekend in Zesco’s 4-2 victory over Power Dynamos in the Charity Shield semi-finals.
Zesco reached the semi-finals of the 2016 CAF Champions League and finished runner’s up to Zanaco in the 2016 Zambian Super League.