The Silver Arrows have won all three races since the summer break courtesy of Lewis Hamilton, who has opened up a 28-point lead at the top of the World Championship standings.
And Wolff is hoping to put on another strong display in front of their sponsors Petronas.
“This will be a weekend with great resonance for us: we have a very close relationship with the country, thanks to our friends at Petronas, and the race has given us many moments of drama and glory over the years,” Wolff said in his usual race preview.
“Our record there in recent seasons has been mixed but the fundamental characteristics of the circuit, with its sweeping corners and long straights, should mean the car is well-suited to the circuit.
“The weather conditions are challenging for the cars, the tyres, the drivers and the team personnel and can often complicate the overall picture; good reliability will be crucial in every aspect of our operations.
“But it goes without saying that our target is to deliver a winning performance to mark the final Grand Prix at Sepang – and to build on the good momentum we have enjoyed since the summer break.”