Sharks head coach Robert du Preez has made three changes to his starting side that will face the Lions in Super Rugby at Ellis Park.
Garth April comes in for Clement Poitrenaud at full-back while Daniel du Preez is at number eight, with Tera Mtembu shifting to the openside.
In the final alteration to the team, Thomas du Toit replaces Tendai Mtawarira at loosehead prop, who is not considered due to a family death.
Sharks: 15 Garth April, 14 Kobus van Wyk, 13 Lukhanyo Am, 12 Andre Esterhuizen, 11 Lwazi Mvovo, 10 Curwin Bosch, 9 Cobus Reinach, 8 Daniel du Preez, 7 Jean-Luc du Preez, 6 Tera Mtembu (c), 5 Ruan Botha, 4 Etienne Oosthuizen, 3 Coenie Oosthuizen, 2 Chiliboy Ralepelle, 1 Thomas du Toit
Replacements: 16 Franco Marais, 17 Juan Schoeman, 18 Lourens Adriaanse, 19 Stephan Lewies, 20 Jacques Vermeulen, 21 Michael Claassens, 22 Inny Radebe, 23 Jeremy Ward
Date: Saturday, April 1
Venue: Emirates Airline Park, Johannesburg
Kick-off: 17:15 local (15:15 GMT)
Referee: Jaco van Heerden (South Africa)
Assistant Referees: Jaco Peyper (South Africa), AJ Jacobs (South Africa)
TMO: Johan Greeff (South Africa)