Dortmund have been in fine form this season, winning four out of five Bundesliga ties, only dropping points in their 0-0 away draw to Freiburg, although they also suffered a 3-1 Champions League loss to Tottenham Hotspur.
Their run though saw new BVB boss Peter Bosz become the first coach to not concede in his opening five Bundesliga matches.
Mönchengladbach, meanwhile, come into this tie on the back of two wins, two draws and one loss, having overcome Stuttgart 2-0 at home in their last encounter.
In team news, Dortmund will be without Marcel Schmelzer (ankle ligaments), Eric Durm (hip), Jeremy Toljan (muscle problems), Marc Bartra (muscle problems), Marco Reus (ankle ligaments), Sebastian Rode (pubic bone), Raphaël Guerreiro (foot) and Andre Schürrle (thigh).
Gladbach are missing Yann Sommer (knee), Tobias Strobl (knee ligaments), Ibrahima Traore (thigh), Vincenzo Grifo (knee), Laszlo Benes (metatarsal) and Josip Drmic (knee).